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Pulseless Electrical Activity (also known by the older term Electromechanical Dissociation or Non-Perfusing Rhythm) refers to any heart rhythm observed on the electrocardiogramAn electrocardiogram (ECG or EKG, abbreviated from the German Elektrokardiogramm) is a graphic produced by an electrocardiograph, which records the electrical activity of the heart over time. Analysis of the various waves and normal vectors of depolarization and repolarization yields important diagnostic information. ...electrocardiogram that should be producing a pulseIn medicine, a person's pulse is the throbbing of their arteries as an effect of the heart beat. It can be felt at the neck (carotid artery), at the wrist (radial artery), behind the knee (Popliteal artery), on the inside of the elbow (Brachial artery), near the ankle joint (Posterior Tibial artery), and a few other places. Pressure waves move through the blood vessels, which are pliable; these waves are not caused by the forward movement of the blood. When the heart contracts, blood is ejected into the aorta and ...pulse, but is not. The condition may or may not be caused by electromechanical dissociation. The most common cause is hypovolemiaIn physiology and medicine, hypovolemia (also hypovolaemia) is a state of decreased blood volume; more specifically, decrease in volume of blood plasma.hypovolemia.

The normal condition when electrical activation of muscle cells precedes mechanical contraction is known as Electromechanical Coupling.

The approach in treatment of PEA is to treat the underlying cause. These possible causes are remembered as the Hs and Ts.

  • HypovolemiaIn physiology and medicine, hypovolemia (also hypovolaemia) is a state of decreased blood volume; more specifically, decrease in volume of blood plasma.Hypovolemia
  • HypoxiaHypoxia literally means "deficient in oxygen." It can refer to: * Hypoxia (medical), a shortage of oxygen in the body. Hypoxaemia is the reduction of oxygen specifically in the blood; anoxia is when there is no oxygen available at all. ** Environmental hypoxia, a condition in high altitudes such as mountains where the reduced partial pressure of oxygen available leads to hypoxia. ** Ischemia, a restriction in blood supply (and therefore ...Hypoxia
  • Hydrogen|- | Triple point || 13.8033 K, 7.042 kPa (Bohr radius) |- | 2H || 0.0115% || colspan="4" | H is stable with 1 neutron Hydrogen (IPA: , is a chemical element represented by the symbol H and an atomic number of 1. At standard temperature and pressure it is a colorless, odorless, nonmetallic, tasteless, highly flammable diatomic gas (H2). With an atomic mass of 1.00794 g/mol, hydrogen ...Hydrogen ions (AcidosisAcidosis is an increased acidity (i.e. an increased hydrogen ion concentration). If not further qualified, it refers to acidity of the blood plasma. Generally, acidosis is said to occur when arterial pH falls below 7.35, while its counterpart (alkalosis) occurs at a pH over 7.45. Arterial blood gas analysis and other tests are required to separate the main causes. Strictly speaking, the term acidemia would be more appropriate ...Acidosis)
  • HypothermiaHypothermia is a condition in which an organism's temperature drops below that required for normal metabolism and bodily function. In warm-blooded animals, core body temperature is maintained near a constant level through biologic homeostasis. But when the body is exposed to cold its internal mechanisms may be unable to replenish the heat that is being lost to the organism's surroundings. Hypothermia is the opposite of hyperthermia. Because the words sound ...Hypothermia
  • HyperkalemiaHyperkalemia (AE) or Hyperkalaemia (BE) is an elevated blood level (above 5.0 mmol/L) of the electrolyte potassium. The prefix hyper- means high (contrast with hypo-, meaning low). The middle kal refers to kalium, which is Latin for potassium. The end portion of the word, -emia, means "in the blood". Extreme degrees of hyperkalemia are considered a medical emergency due to the ...Hyperkalemia or HypokalemiaHypokalemia is a potentially fatal condition in which the body fails to retain sufficient potassium to maintain health. The condition is also known as potassium deficiency. The prefix hypo- means low (contrast with hyper-, meaning high). The middle kal refers to kalium, ...Hypokalemia
  • HypoglycemiaHypoglycemia (hypoglycæmia in the UK) is a medical term referring to a pathologic state produced by a lower than normal level of sugar (glucose) in the blood. The term hypoglycemia literally means "under-sweet blood" (Gr. hypo-, glykys, haima). Hypoglycemia can produce a variety of symptoms and effects but the principal problems arise from an inadequate supply of glucose as fuel to the brain, resulting in ...Hypoglycemia
  • TabletsA tablet is a mixture of active substances and excipients, usually in powder form, pressed or compacted into a solid. The excipients include binders, glidants (flow aids) and lubricants to ensure efficient tabletting; disintegrants to ensure that the tablet breaks up in the digestive tract; sweetners or flavours to mask the taste of bad-tasting ...Tablets or ToxinsCategory:Toxicology Category:Poisons Category:Biomolecules Category:Virulence factors ar:تصنيف:سموم nl:Categorie:Toxische stof pl:Kategoria:ToksynyToxins (Drug overdoseNo quick definition available. Drug overdose)
  • Cardiac TamponadeCardiac tamponade, also known as pericardial tamponade, is a medical emergency condition in which fluid accumulates in the pericardium (the sac in which the heart is enclosed). The elevated pericardial pressure puts significant pressure on the heart, ...Cardiac Tamponade
  • Tension pneumothoraxA tension pneumothorax is a life-threatening condition that results from a progressive deterioration and worsening of a simple pneumothorax, associated with the formation of a one-way valve at the point of rupture. Upon inspiration, when the pressure inside the chest and pleural cavity lessens as a result of the respiratory muscles increasing chest dimensions, air is sucked ...Tension pneumothorax
  • ThrombosisThrombosis is the formation of a clot or thrombus inside a blood vessel, obstructing the flow of blood through the circulatory system. Thromboembolism is a general term describing both thrombosis and its main complication which is embolisation.Thrombosis (Myocardial infarctionAcute myocardial infarction (AMI or MI), more commonly known as a heart attack, is a disease state that occurs when the blood supply to a part of the heart is interrupted. The resulting ischemia or oxygen shortage causes damage and potential death of heart tissue. It is a medical emergency, and the leading cause of death for both men and women all over the world. Important risk factors are a previous history ...Myocardial infarction)
  • ThrombosisThrombosis is the formation of a clot or thrombus inside a blood vessel, obstructing the flow of blood through the circulatory system. Thromboembolism is a general term describing both thrombosis and its main complication which is embolisation.Thrombosis (Pulmonary embolismPulmonary embolism (PE) is blockage of the pulmonary artery (or one of its branches), usually when a venous thrombus (blood clot from a vein), becomes dislodged from its site of formation and embolizes to the arterial blood supply of one of the lungs. This process is termed thromboembolism. Symptoms may include difficulty breathing, pain in the chest during breathing, and in more severe cases collapse, circulatory instability and sudden death. Treatment, usually, is with anticoagulant medication, such as heparin and ...Pulmonary embolism)
  • Trauma:Treatment of physical trauma is described here and in First aid. For medical guidelines, see Guideline (medical). Physical trauma refers to a physical injury. A trauma patient is someone who has suffered serious and life-threatening physical injury potentially resulting in secondary complications such as shock, respiratory failure and death.Trauma (HypovolemiaIn physiology and medicine, hypovolemia (also hypovolaemia) is a state of decreased blood volume; more specifically, decrease in volume of blood plasma.Hypovolemia from blood loss)

Where an underlying systemic cause is unable to be determined in sufficient time, pulseless electrical activity should receive treatment methods as if the patient were in asystoleIn medicine, asystole is a state of no cardiac electrical activity, hence no contractions of the myocardium and no cardiac output or blood flow. Asystole is one of the conditions required for a medical practitioner to certify death. In asystole, the heart will not respond to defibrillation because it is already depolarized, however some emergency physicians advocate a trial of defibrillation in case the rhythm is actually fine ventricular fibrillation, ...asystole. Treatment is intravenous delivery EpinephrineEpinephrine (INN) (IPA: ) or adrenaline (European Pharmacopoeia and BAN) (IPA: ), sometimes spelled "epinephrin" or "adrenalin" respectively, is a hormone. It is a catecholamine, a sympathomimetic monoamine derived from the amino acids phenylalanine and tyrosine. ...Epinephrine 1 mg every 3-5 minutes, and, if the underlying rhythm is bradycardiaBradycardia, as applied to adult medicine, is defined as a resting heart rate of under 60 beats per minute, though it is seldom symptomatic until the rate drops below 50 beat/min. Sinus Bradycardia eMedicine Trained athletes tend to have slow resting heart rates, and resting ...bradycardia, AtropineAtropine is a tropane alkaloid extracted from the deadly nightshade (Atropa belladonna) and other plants of the family Solanaceae. It is a secondary metabolite of these plants and serves as a drug with a wide variety of effects. Being potentially deadly, it derives its name from Atropos, one of the three Fates who, according to Greek mythology, chose how a person was to die.Atropine 1 mg IV up to .04 mg/kg (varies with regional protocols). Both these drugs should be administered along with appropriate CPRCardiopulmonary resuscitation (CPR) is an emergency medical procedure for a victim of cardiac arrest or, in some circumstances, respiratory arrest. CPR is performed in hospitals, or in the community by laypersons or by emergency response professionals. CPR consists of artificial blood circulation and artificial respiration (i.e. chest compressions and lung ventilation). CPR is generally continued, usually in the presence of advanced life support, ...CPR techniques. DefibrillatorsDefibrillation is the definitive treatment for the life-threatening cardiac arrhythmias ventricular fibrillation and pulseless ventricular tachycardia. Defibrillation consists of delivering a therapeutic dose of electrical energy to the affected heart with a device called a defibrillator. This depolarizes a critical mass of the heart muscle, terminates the arrhythmia, ...Defibrillators are not used for this rhythm, as the problem lies in the response of the myocardial tissue to electrical impulses.


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